Really dumb question, but did Qiagen revive pyrosequencing when I wasn't looking?
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Looks like they did. No obvious announcements/comments from pundits anywhere either (google does not seem to bring anything up other than Qiagen's own site). Must be an application specific release.
The PyroMark Q24 is highly suited for the analysis of CpG methylation, SNPs, insertion/deletions, STRs, variable gene copy number, as well as for microbial identification and resistance typing.Last edited by GenoMax; 12-18-2018, 08:54 AM. -
QIAGEN bought Biotage (what was Pyrosequencing AB and the original outlicencing entity for the IP) in 2008. The PyroMark assays have been available from QIAGEN for about that length of time from marketing materials. I'm not sure pyrosequencing ever really went away.Comment
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Thanks - so for these specific applications, it's still here.Originally posted by Bukowski View PostComment
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM
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