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Hi, We are currently moving our amplicon sequencing library prep over to an automatic platform. Before outlaying for machinery and programming, can anyone advise of positive or negative experiences with the different platforms available. We currently have in house Epimotion 5075 and Hamilton Microlab StarLet. We would like to automate magnetic bead clean up for each of the PCR's and pooling/quantification. Currently, our first attempts to get the Hamilton up and running have been quite disappointing so I would like to know if it is worth persevering?
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Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM -
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...05-22-2026, 06:42 AM