Hi, We are currently moving our amplicon sequencing library prep over to an automatic platform. Before outlaying for machinery and programming, can anyone advise of positive or negative experiences with the different platforms available. We currently have in house Epimotion 5075 and Hamilton Microlab StarLet. We would like to automate magnetic bead clean up for each of the PCR's and pooling/quantification. Currently, our first attempts to get the Hamilton up and running have been quite disappointing so I would like to know if it is worth persevering?
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NGS has revolutionized clinical microbiology by offering new ways to identify and surveil pathogens without prior knowledge of the target. One popular approach is 16S rRNA and ITS amplicon sequencing, which targets specific microbial markers. But studies are increasingly incorporating shotgun metagenomics, a technique that sequences all DNA from a sample without targeting specific microbial markers. This approach allows more detailed taxonomic classification,...10-30-2026, 06:46 AM -
Tumors contain complex mixtures of cell populations that evolve in response to treatment and host-specific factors. Tissue biopsies provide only static snapshots of a tumor’s state. But what if we could follow that evolution over time using a minimally invasive technique?
Liquid biopsies can detect tumor-derived material circulating in the bloodstream, providing a way to study treatment response, detect emerging resistance, and discover new biomarkers. Circulating...10-14-2026, 09:55 AM