Hi, We are currently moving our amplicon sequencing library prep over to an automatic platform. Before outlaying for machinery and programming, can anyone advise of positive or negative experiences with the different platforms available. We currently have in house Epimotion 5075 and Hamilton Microlab StarLet. We would like to automate magnetic bead clean up for each of the PCR's and pooling/quantification. Currently, our first attempts to get the Hamilton up and running have been quite disappointing so I would like to know if it is worth persevering?
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM -
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...07-20-2026, 11:48 AM