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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,673 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,612 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by cycomatto, 12-20-2011, 11:53 AM
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7 responses
17,317 views
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by xied75
01-22-2013, 04:42 AM
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Started by amarth, 01-21-2013, 01:15 PM
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1 response
1,674 views
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by sisch
01-22-2013, 04:24 AM
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Started by spark, 12-26-2011, 10:01 AM
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7 responses
5,240 views
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by Robby
01-22-2013, 02:45 AM
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Started by M.Verma, 01-21-2013, 09:12 PM
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1 response
1,192 views
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by dpryan
01-22-2013, 02:33 AM
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Started by desmo, 01-21-2013, 03:28 AM
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4 responses
2,904 views
0 reactions
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by desmo
01-22-2013, 12:57 AM
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Started by priesgo, 01-17-2013, 02:49 AM
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5 responses
2,327 views
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by priesgo
01-22-2013, 12:10 AM
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Started by Richard.Y, 01-21-2013, 11:03 PM
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0 responses
1,091 views
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by Richard.Y
01-21-2013, 11:03 PM
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Started by Salmon, 01-13-2011, 08:27 AM
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2 responses
3,926 views
0 reactions
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by A_Morozov
01-21-2013, 10:38 PM
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Started by kvk727, 01-10-2013, 05:50 PM
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1 response
1,755 views
0 reactions
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by Gordon Smyth
01-21-2013, 02:31 PM
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Started by steve.eis, 12-11-2012, 07:18 AM
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3 responses
12,121 views
0 reactions
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Last Post
by Gordon Smyth
01-21-2013, 02:16 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 07:41 AM
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12 views
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by SEQadmin2
Yesterday, 07:41 AM
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Started by SEQadmin2, 08-03-2026, 10:13 AM
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25 views
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by SEQadmin2
08-03-2026, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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38 views
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by SEQadmin2
07-31-2026, 02:55 AM
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