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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,649 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,394 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Saint-Louis, 01-18-2013, 11:30 AM
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37 views
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by Saint-Louis
01-18-2013, 11:30 AM
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Started by hmaa, 09-15-2012, 02:24 AM
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18 responses
4,150 views
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by marcowanger
01-18-2013, 09:15 AM
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Started by ilya.kuzovkin, 01-18-2013, 08:38 AM
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1 response
1,890 views
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Started by chongm, 01-18-2013, 08:37 AM
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1,161 views
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by chongm
01-18-2013, 08:37 AM
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Started by markero, 01-18-2013, 02:05 AM
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1 response
1,406 views
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by henry.wood
01-18-2013, 07:27 AM
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Started by shadow19c, 01-02-2013, 07:05 AM
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3 responses
1,958 views
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by shadow19c
01-18-2013, 05:38 AM
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Started by Vasilisa, 01-16-2013, 07:06 AM
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2 responses
2,176 views
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by Vasilisa
01-18-2013, 05:37 AM
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Started by zxybl, 08-05-2010, 10:27 AM
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4 responses
4,050 views
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by zxybl
01-18-2013, 05:16 AM
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Started by ryanmcg, 12-05-2012, 09:18 AM
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4 responses
1,661 views
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by msalm
01-18-2013, 05:11 AM
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Started by Karenj, 01-18-2013, 03:10 AM
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0 responses
1,264 views
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by Karenj
01-18-2013, 03:10 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 10:13 AM
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5 views
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by SEQadmin2
Today, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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20 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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17 views
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by SEQadmin2
07-24-2026, 12:17 PM
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