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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,286 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
682,454 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Arupsss, 08-16-2012, 07:03 AM
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3 responses
2,458 views
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by Arupsss
08-16-2012, 11:10 AM
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Started by skblazer, 08-16-2012, 10:31 AM
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0 responses
1,255 views
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by skblazer
08-16-2012, 10:31 AM
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Started by m_elena_bioinfo, 11-04-2011, 02:06 AM
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14 responses
6,754 views
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by yeppomonkey
08-16-2012, 09:36 AM
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Started by turnersd, 08-14-2012, 08:36 AM
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4 responses
4,341 views
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by mudshark
08-16-2012, 07:31 AM
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Started by biologist, 08-16-2012, 06:35 AM
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0 responses
963 views
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by biologist
08-16-2012, 06:35 AM
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Started by Splinter479, 08-16-2012, 01:54 AM
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1 response
1,213 views
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by colindaven
08-16-2012, 02:40 AM
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Started by obig, 01-13-2011, 07:43 PM
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9 responses
6,984 views
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Last Post
by Simon Anders
08-15-2012, 11:43 PM
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Started by Sun-SEQ, 08-15-2012, 09:13 PM
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0 responses
1,836 views
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Last Post
by Sun-SEQ
08-15-2012, 09:13 PM
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Started by Dario1984, 08-15-2012, 06:00 PM
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0 responses
1,095 views
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by Dario1984
08-15-2012, 06:00 PM
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Started by NKAkers, 08-13-2012, 04:40 PM
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1 response
2,117 views
0 reactions
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Last Post
by NKAkers
08-15-2012, 05:40 PM
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by SEQadmin2
Childhood cancers, effectively fatal 60 years ago, are now curable for up to 85% of children with access to contemporary treatments and...-
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05-08-2026, 01:42 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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Channel: Articles
Today, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
Channel: Articles
06-18-2026, 07:11 AM -
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by SEQadmin2
Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
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Channel: Articles
06-02-2026, 10:05 AM -
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Started by SEQadmin2, Yesterday, 05:37 AM
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0 responses
7 views
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Last Post
by SEQadmin2
Yesterday, 05:37 AM
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Started by SEQadmin2, 06-26-2026, 11:10 AM
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0 responses
17 views
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Last Post
by SEQadmin2
06-26-2026, 11:10 AM
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Whole-Genome Sequencing Traces Faroe Islands Ancestry to a North Atlantic Founder Population
by SEQadmin2
Started by SEQadmin2, 06-17-2026, 06:09 AM
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0 responses
52 views
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Last Post
by SEQadmin2
06-17-2026, 06:09 AM
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