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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,657 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,457 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by shawpa, 01-20-2012, 05:00 AM
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2 responses
4,115 views
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by Petr
01-25-2012, 06:18 AM
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Started by HGENETIC, 01-25-2012, 04:19 AM
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0 responses
2,865 views
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by HGENETIC
01-25-2012, 04:19 AM
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Started by kortschak, 01-24-2012, 10:59 PM
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0 responses
1,899 views
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by kortschak
01-24-2012, 10:59 PM
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Started by oiiio, 01-24-2012, 09:29 PM
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1,855 views
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by oiiio
01-24-2012, 09:29 PM
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Started by rnathg, 01-24-2012, 07:46 PM
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0 responses
3,771 views
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by rnathg
01-24-2012, 07:46 PM
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Started by fkrueger, 01-29-2011, 01:29 PM
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17 responses
11,684 views
0 reactions
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by amitra
01-24-2012, 06:29 PM
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Started by Dario1984, 01-24-2012, 05:00 PM
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0 responses
1,949 views
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by Dario1984
01-24-2012, 05:00 PM
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Started by feng, 01-24-2012, 02:48 PM
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0 responses
1,166 views
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by feng
01-24-2012, 02:48 PM
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Started by Noa, 01-24-2012, 06:42 AM
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2 responses
3,887 views
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by Noa
01-24-2012, 01:33 PM
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Started by kjaja, 01-24-2012, 11:26 AM
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0 responses
1,383 views
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by kjaja
01-24-2012, 11:26 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 10:13 AM
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14 views
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by SEQadmin2
Yesterday, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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27 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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20 views
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by SEQadmin2
07-24-2026, 12:17 PM
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