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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,714 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,520 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by IrisZhu, 08-10-2010, 05:40 AM
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21 responses
15,573 views
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by Sol
03-05-2011, 04:04 PM
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Started by rudi283, 03-02-2011, 06:46 AM
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4 responses
11,539 views
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by rudi283
03-05-2011, 11:49 AM
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Assembling De Novo 454 Transcriptome Contigs and Singletons with Illumina Short Reads
by Vickenstein
Started by Vickenstein, 03-01-2011, 07:44 AM
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7 responses
6,250 views
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Last Post
by BaCh
03-05-2011, 01:43 AM
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Started by BaCh, 03-04-2011, 05:57 AM
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4 responses
3,618 views
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by NextGenSeq
03-04-2011, 01:06 PM
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Started by polarise, 02-17-2011, 06:29 AM
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3 responses
3,677 views
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Started by libiyagirl, 03-03-2011, 03:33 PM
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5 responses
3,316 views
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by libiyagirl
03-04-2011, 12:27 PM
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Started by Nick, 03-04-2011, 10:17 AM
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1 response
2,299 views
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by paulr
03-04-2011, 11:58 AM
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Started by dicty, 03-04-2011, 08:09 AM
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1 response
2,390 views
0 reactions
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by NextGenSeq
03-04-2011, 08:38 AM
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Started by KevinLam, 03-03-2011, 09:09 PM
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2 responses
2,769 views
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by KevinLam
03-04-2011, 07:36 AM
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Started by ameyer, 02-24-2011, 08:20 AM
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1 response
1,914 views
0 reactions
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Last Post
by jtrivino
03-04-2011, 06:07 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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0 responses
15 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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0 responses
23 views
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by SEQadmin2
08-18-2026, 10:05 AM
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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0 responses
42 views
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by SEQadmin2
08-13-2026, 12:22 PM
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