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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,478 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,731 views
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by ECO
12-25-2009, 06:45 PM
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Started by GB1, 04-26-2017, 06:56 AM
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by GB1
04-26-2017, 06:56 AM
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Started by CraigRepositive, 04-26-2017, 06:06 AM
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1,792 views
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Started by RoMI95, 02-17-2017, 01:08 AM
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2 responses
2,065 views
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CAP3 - strange behaviour, never finishes running (2xXeon 2620v4/Ubuntu 16.04.2 LTS)
by Timofey Skvortsov
Started by Timofey Skvortsov, 04-25-2017, 01:03 AM
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2 responses
1,874 views
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Started by SeqTroubles, 04-24-2017, 04:55 AM
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4 responses
7,811 views
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Started by Grenouille, 06-05-2013, 03:50 AM
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7 responses
3,058 views
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by tanaybhatt
04-25-2017, 03:58 AM
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Started by kamalnaini, 04-24-2017, 07:58 PM
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0 responses
1,302 views
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by kamalnaini
04-24-2017, 07:58 PM
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Started by quantic, 04-19-2017, 01:15 PM
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1 response
3,666 views
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Started by Zapages, 06-29-2015, 03:06 PM
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6 responses
2,859 views
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by av299
04-24-2017, 07:59 AM
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Started by my9569, 04-23-2017, 05:28 PM
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1 response
1,148 views
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by GenoMax
04-24-2017, 07:48 AM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, 07-13-2026, 10:26 AM
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20 views
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by SEQadmin2
07-13-2026, 10:26 AM
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Started by SEQadmin2, 07-09-2026, 10:04 AM
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by SEQadmin2
07-09-2026, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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