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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
105,471 views
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by Guest
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
673,290 views
1 like
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by ECO
12-25-2009, 06:45 PM
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Started by mrfox, 07-17-2015, 11:22 AM
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4 responses
2,637 views
0 likes
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Last Post
by mrfox
09-09-2015, 06:43 PM
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Started by cmccabe, 09-09-2015, 02:30 PM
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0 responses
1,284 views
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by cmccabe
09-09-2015, 02:30 PM
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Started by IsBeth, 09-09-2015, 03:12 AM
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1 response
1,253 views
0 likes
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Last Post
by dpryan
09-09-2015, 01:09 PM
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Started by GeGnome, 04-19-2012, 12:38 PM
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3 responses
3,171 views
0 likes
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Last Post
by scalabrin
09-09-2015, 05:41 AM
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Started by wjeck, 10-15-2009, 02:34 PM
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26 responses
15,756 views
0 likes
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Last Post
by simobioinfo
09-09-2015, 05:37 AM
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Started by Saeideh, 09-09-2015, 03:13 AM
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0 responses
1,041 views
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Last Post
by Saeideh
09-09-2015, 03:13 AM
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Started by dawn1313, 09-08-2015, 09:27 AM
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0 responses
1,005 views
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Last Post
by dawn1313
09-08-2015, 09:27 AM
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Started by annrose, 09-08-2015, 07:29 AM
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1 response
1,410 views
0 likes
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Last Post
by GenoMax
09-08-2015, 09:07 AM
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Started by Saeideh, 09-08-2015, 03:26 AM
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2 responses
1,133 views
0 likes
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Last Post
by GenoMax
09-08-2015, 08:59 AM
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Started by NikTuzov, 09-08-2015, 08:04 AM
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1 response
1,941 views
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Last Post
by HESmith
09-08-2015, 08:41 AM
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...-
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