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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,381 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,318 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by k.devito, 07-31-2014, 03:20 AM
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4 responses
1,807 views
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by k.devito
07-31-2014, 05:23 AM
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Started by dovah, 07-31-2014, 04:36 AM
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0 responses
1,945 views
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by dovah
07-31-2014, 04:36 AM
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Started by hbt, 07-31-2014, 03:41 AM
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4 responses
1,514 views
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by hbt
07-31-2014, 04:28 AM
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Started by jschuur1, 03-18-2011, 05:06 AM
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6 responses
4,608 views
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by enrico
07-31-2014, 03:43 AM
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Started by paolo.kunder, 07-31-2014, 03:21 AM
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0 responses
1,130 views
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by paolo.kunder
07-31-2014, 03:21 AM
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Started by super0925, 07-31-2014, 02:25 AM
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0 responses
1,322 views
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by super0925
07-31-2014, 02:25 AM
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Started by Mike2188, 07-30-2014, 02:48 PM
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0 responses
1,579 views
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by Mike2188
07-30-2014, 02:48 PM
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Started by chpawan, 03-02-2014, 08:01 AM
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3 responses
2,152 views
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by Mike2188
07-30-2014, 02:04 PM
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Started by BFM, 07-30-2014, 12:52 PM
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0 responses
1,284 views
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by BFM
07-30-2014, 12:52 PM
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Started by bioinfobeginner, 07-30-2014, 08:22 AM
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0 responses
1,335 views
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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