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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,663 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,509 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by mdb@wistar, 01-30-2013, 03:56 PM
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6 responses
2,198 views
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by mdb@wistar
02-04-2013, 11:51 AM
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Started by mdb@wistar, 02-01-2013, 08:39 AM
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2 responses
2,965 views
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by mdb@wistar
02-04-2013, 11:50 AM
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Started by unique379, 02-04-2013, 06:10 AM
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3 responses
1,639 views
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by dpryan
02-04-2013, 09:12 AM
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Started by pfranchini, 02-04-2013, 03:51 AM
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0 responses
1,471 views
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by pfranchini
02-04-2013, 03:51 AM
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Started by MenzZana, 02-01-2013, 12:15 AM
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2 responses
2,553 views
0 reactions
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by MenzZana
02-04-2013, 01:41 AM
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Started by papori, 02-03-2013, 11:00 PM
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0 responses
1,047 views
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by papori
02-03-2013, 11:00 PM
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Started by caswater, 02-03-2013, 02:41 PM
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0 responses
1,342 views
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by caswater
02-03-2013, 02:41 PM
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Started by gfmgfm, 12-15-2010, 03:39 AM
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8 responses
4,624 views
0 reactions
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by soban
02-03-2013, 10:01 AM
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Started by sonja, 02-01-2013, 08:26 AM
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8 responses
4,057 views
0 reactions
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by sonja
02-03-2013, 09:59 AM
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Started by lukas1848, 01-31-2013, 09:40 AM
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5 responses
11,134 views
0 reactions
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Last Post
by yzzhang
02-03-2013, 07:55 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-03-2026, 10:13 AM
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0 responses
15 views
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by SEQadmin2
08-03-2026, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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0 responses
32 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
23 views
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by SEQadmin2
07-24-2026, 12:17 PM
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