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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,631 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,315 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by baohua100, 05-10-2011, 11:32 PM
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0 responses
2,409 views
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by baohua100
05-10-2011, 11:32 PM
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Started by Vinz, 05-10-2011, 10:38 PM
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0 responses
2,403 views
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by Vinz
05-10-2011, 10:38 PM
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Started by fc_c, 05-10-2011, 09:21 PM
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1,359 views
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by fc_c
05-10-2011, 09:21 PM
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Started by chip_seq, 04-18-2011, 12:11 AM
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14 responses
4,382 views
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by chip_seq
05-10-2011, 07:51 PM
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1 response
1,700 views
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by maubp
05-10-2011, 01:54 PM
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Started by dp05yk, 05-10-2011, 12:37 PM
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0 responses
1,520 views
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by dp05yk
05-10-2011, 12:37 PM
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Started by Esther, 07-27-2010, 05:40 AM
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4 responses
2,423 views
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by nilshomer
05-10-2011, 12:29 PM
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Started by kursuni, 05-10-2011, 11:59 AM
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0 responses
1,452 views
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by kursuni
05-10-2011, 11:59 AM
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Started by pi101, 05-10-2011, 11:20 AM
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0 responses
2,161 views
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by pi101
05-10-2011, 11:20 AM
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Started by Protaeus, 05-10-2011, 10:06 AM
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0 responses
2,852 views
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by Protaeus
05-10-2011, 10:06 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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0 responses
18 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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15 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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14 views
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by SEQadmin2
07-23-2026, 11:41 AM
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